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01/05/09
Corticosteroids occur naturally and in a host of many variations. The first corticosteroid that was ever discovered was cortisol. This substance is produced in the adrenal glands of most mammals that walk the planet.
Corticosteroids are key in the management of various conditions that include diseases like asthma, diseases of the bowel, and autoimmune disorders. The sustained use of these substances has been linked to the onset of various side effects and these have been noted to include various conditions like the outset of pituitary axis suppression, disturbances in the electrolyte balance, and hyperglycemia. These are amongst the most adverse of symptoms that come with the prolonged use of these substances.
Corticosteroids are very helpful in their inhaled form as these are used to manage conditions like asthma and other pulmonary chronic diseases. As such, many people rely on these medications and there is little doubt that the use of these medicines has served to make the lives of these individuals bearable. However, there is much controversy with regard to the effect that the use of these medicines on the body. This issue is with regard to the deterioration of the bone structure otherwise referred to as osteoporosis. Research has been carried out to ascertain these concerns and the results are quite an ease on the worries of many. Cases of reduction in the density of the bones have only been reported in persons who have inhaled these steroids for many years. This has offered the much needed credibility to these medications and now it can be safely concluded that the benefits far outstrip the negatives that may be accrued with the use of these medications.
It is prudent that as much information about the net effects of using these substances be offered courtesy of the numerous research studies that have been carried out on the subject. The studies have revealed that the use of corticosteroids brings alterations in the necrotic system of the bones and this is specifically in the trabecular system. This results in the reduced content of calcium serum and also the fact that there is a decrease in the development of bones in the body. Patients especially those who are in the postmenopausal stage of life are presented with a greater risk of bone fracture.
The most critical risk that has been linked to the use of corticosteroids is without doubt that of osteoporosis. The most urgent issue is how the condition is managed before it can get out of hand. The best way forward is for patients to seek the advice and testing capabilities of orthopedists such that the effects of osteoporosis can be curtailed at an early stage courtesy of prophylactic actions.
There are several ways in which the ravaging effects of the bone disease can be downsized to manageable amounts. First of all it has to do with the nutritional aspects. The person concerned should make an effort to provide as much vitamin D to the body. The same case applies for calcium supplements.





