Breast development does involve coordinated efforts of ovarian and pituitary hormones and also makes use of other local mediators. The effects of the steroidal hormone estrogen on the growth of breasts are also a result circulating estradiol units as well as other locally formed estrogens. In this case an increase in the activity of enzyme is able to increase concentrations of estrogen which then initiates the development of breasts males as well as females. So as much as androgens do not have the ability to stimulate the development of breasts directly, it is possible to do so if they can be aromatized to the hormone estrogen.

This is evident in cases where androgen is in excess or other cases where there patients who have a high activity of aromatose.  In fact gynecomastia which means the development of breasts in males begins in three phases of the individual’s life. The initial one is the phase that commences immediately after the birth of a baby. In this case it occurs both in females and males. This is created in the body of the mother in terms of pregnancy that brings about a stimulation of the breast tissue in a newborn. Puberty also marks the onset of the consecutive situation in where gynecomastia occurs physiologically. Boys are known to contain detectable cases of gynecomastia at the age of 14 years.

In early cases of puberty, the gland pituitary does release the hormone gonadotropins which then stimulate the testicles to produce testosterone most of the days at night. Estrogen rises throughout the whole day. In addition, some studies have indicated that a small estrogen to androgen ratio do exist in male boys in the cases of pubertal gynecomastia as when compared to boys in which gynecomastia does not develop.  Since the growth of tissue in breast tissue of males takes place in analogous fashions as compared to that of females, the exact hormone which affects breast tissue in females could cause gynecomastia. This makes estrogen excesses derived from an overproduction to initiate a cascade of breasts. Aside from the case of tumors, there are conditions which are associated highly with an excessive aromatization which occurs when testosterone and the steroidal hormone androgen, has been aromatized to estrogen thus leading to a case of acute gynecomastia.

In addition to this, a familiar stronger case of gynecomastia where there are cases of para-gonadal activity of aromatization discovered lately.  In addition, high cases of hyperthyroidism do induce cases of gynecomastia via a couple of mechanisms, which include such cases of high levels of aromatose activity. Another probable result of acute gynecomastia which comes from excesses of estrogen excesses as well as steroidal displacement elements of sex hormones which binds the element globulin.  Any condition of drug activity that displaces steroids will automatically be able to displace estrogen causing estrogen levels to circulate more readily. In essence an equilibrium do exist where androgen as well as estrogen work hand in hand to prevent the growth associated with breast tissues where any increase in levels of estrogen or reductions in the levels androgen could tip odds towards a case of gynecomastia.

If you like this article, click here to share: