Breast development does involve coordinated efforts of ovarian and pituitary hormones and also makes use of other local mediators. The effects of the steroidal hormone estrogen on the growth of breasts are also a result circulating estradiol units as well as other locally formed estrogens. In this case an increase in the activity of enzyme is able to increase concentrations of estrogen which then initiates the development of breasts males as well as females. So as much as androgens do not have the ability to stimulate the development of breasts directly, it is possible to do so if they can be aromatized to the hormone estrogen. This is evident in cases where androgen is in excess or other cases where there patients who have a high activity of aromatose.  In fact gynecomastia which means the development of breasts in males ...

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